Principle of the test
THE GASEOUS EXCHANGE
When breathing, we inhale oxygen and exhale carbon dioxide, generating an exchange
of gases between the pulmonary alveoli and the blood. If there is any type of tumor in the patient's
body, the tumor molecules detach and travel through the bloodstream. When the blood reaches the
lungs for oxygenation, gaseous exchange occurs in the alveoli, due to the concentration of gases
inside and outside of the lungs, producing an exchange between the blood and the alveolar air.
What concerns us is the exhaled CO2, since it becomes a means of transport of
Metabolites. Now, oxidative stress is a biochemical situation of imbalance between free radicals and
antioxidant defense mechanisms. Cancer is per se a disease that induces oxidative stress.
Alterations of neoplastic cells and tumor infiltration by inflammatory cells CAN BE DETECTED IN THE
Depending on the type of cancer, each type of tumor releases different types of
TOTALLY DIFFERENT cells and each pathology emits different Volatile Organic Compounds, that is, a
DIFFERENT ODOR, which is why we can clearly differentiate a breath sample with breast cancer against
a shows with lung cancer, etc.
These compounds come in concentrations of PARTS PER MILLION and can only be detected with highly sensitive equipment such as our Electronic Nose: LabiNose 43.